Perfluorooctyl bromide nanoemulsions holding MnO2 nanoparticles with dual-modality imaging and glutathione depletion enhanced HIFU-eliciting tumor immunogenic cell death

Perfluorooctyl bromide nanoemulsions holding MnO2 nanoparticles with dual-modality imaging and glutathione depletion enhanced HIFU-eliciting tumor immunogenic cell death

Tumor-targeted immunotherapy is a remarkable breakthrough, offering the inimitable advantage of specific tumoricidal effects with reduced immune-associated cytotoxicity. However, existing platforms suffer from low efficacy, inability to induce strong immunogenic cell death (ICD), and restrained capa...

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Bibliographic Details
Main Authors: Xinping Kuai, Yuefei Zhu, Zheng Yuan, Shengyu Wang, Lin Lin, Xiaodan Ye, Yiping Lu, Yu Luo, Zhiqing Pang, Daoying Geng, Bo Yin
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Immunogenic cell death
Nanoemulsions
Manganese dioxide nanoparticles
Glutathione depletion
Dual-modality imaging
High-intensity focused ultrasound
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521002744

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http://www.sciencedirect.com/science/article/pii/S2211383521002744

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