M-CSF induces monocyte survival by activating NF-κB p65 phosphorylation at Ser276 via protein kinase C.

Macrophage colony-stimulating factor (M-CSF) promotes mononuclear phagocyte survival and proliferation. The transcription factor Nuclear Factor-kappaB (NF-κB) is a key regulator of genes involved in M-CSF-induced mononuclear phagocyte survival and this study focused at identifying the mechanism of N...

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Bibliographic Details
Main Authors: Yijie Wang, Xiaokui Mo, Melissa G Piper, Hongmei Wang, Narasimham L Parinandi, Denis Guttridge, Clay B Marsh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3245220?pdf=render