Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas.

Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas.

Microarray analysis of promoter hypermethylation provides insight into the role and extent of DNA methylation in the development of colorectal cancer (CRC) and may be co-monitored with the appearance of driver mutations. Colonic biopsy samples were obtained endoscopically from 10 normal, 23 adenoma...

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Bibliographic Details
Main Authors: Árpád V Patai, Gábor Valcz, Péter Hollósi, Alexandra Kalmár, Bálint Péterfia, Árpád Patai, Barnabás Wichmann, Sándor Spisák, Barbara Kinga Barták, Katalin Leiszter, Kinga Tóth, Ferenc Sipos, Ilona Kovalszky, Zoltán Péter, Pál Miheller, Zsolt Tulassay, Béla Molnár
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4546193?pdf=render

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http://europepmc.org/articles/PMC4546193?pdf=render

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