The differential effects of tumor burdens on predicting the net benefits of ssCART-19 cell treatment on r/r B-ALL patients

The differential effects of tumor burdens on predicting the net benefits of ssCART-19 cell treatment on r/r B-ALL patients

Abstract The tumor burden (TB) is significantly related to the severity of cytokine release syndrome (CRS) caused by CAR-T cells, but its correlation with therapeutic efficacy has not been systematically studied. This study focused on the effects of the TB level on both the safety and efficacy of ss...

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Bibliographic Details
Main Authors: Minghao Li, Sheng-Li Xue, Xiaowen Tang, Jiayu Xu, Suning Chen, Yue Han, Huiying Qiu, Miao Miao, Nan Xu, Jingwen Tan, Liqing Kang, Zhou Yu, Xiaoyan Lou, Yang Xu, Jia Chen, Zhiqiang Yan, Weixing Feng, Depei Wu, Lei Yu
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-04296-3

Internet

https://doi.org/10.1038/s41598-021-04296-3

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