The validity and applications of the analgesia nociception index: a narrative review
Pain refers to the subjective, unpleasant experience that is related to illness or injury. In contrast to pain, nociception refers to the physiological neural processing of noxious stimuli, such as intra-operative surgical stimuli. One novel device, the Analgesia Nociception Index (ANI), aims to obj...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Surgery |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1234246/full |
| _version_ | 1797745866592747520 |
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| author | Bill Hum Alexa Christophides Zhaosheng Jin Murad Elias Kamil Taneja Sergio D. Bergese |
| author_facet | Bill Hum Alexa Christophides Zhaosheng Jin Murad Elias Kamil Taneja Sergio D. Bergese |
| author_sort | Bill Hum |
| collection | DOAJ |
| description | Pain refers to the subjective, unpleasant experience that is related to illness or injury. In contrast to pain, nociception refers to the physiological neural processing of noxious stimuli, such as intra-operative surgical stimuli. One novel device, the Analgesia Nociception Index (ANI), aims to objectively measure intra-operative nociception by analyzing the heart rate variability in patients undergoing surgery. Through this method of nociceptive monitoring, the ANI device aims to provide an objective, continuous evaluation of patient comfort levels and allow anesthesiologists to better manage surgical stress and patient analgesia, perhaps with even better efficacy than current practices used to assess nociception. Additionally, ANI may have clinical application in settings outside of the operating room, such as in the intensive care unit. In this narrative review, we compiled and summarized the findings of many studies that have investigated ANI's validity and applications in different clinical settings. Currently, the literature appears mostly supportive of ANI's ability to detect nociception in both surgical and non-surgical settings. However, the ability for ANI to provide clinical benefits, such as decreased intra-operative opioid use, post-operative opioid use, and post-operative pain compared to standard practices appear controversial. Because of the wide variety of methodology, clinical settings, patient populations, and limitations in these studies, more investigation of ANI is needed before any firm conclusions can be drawn on its clinical benefits. |
| first_indexed | 2024-03-12T15:29:06Z |
| format | Article |
| id | doaj.art-fa6534f53c8c4d95bb42eb5f21b2f0c2 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-03-12T15:29:06Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-fa6534f53c8c4d95bb42eb5f21b2f0c22023-08-10T09:41:16ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-08-011010.3389/fsurg.2023.12342461234246The validity and applications of the analgesia nociception index: a narrative reviewBill Hum0Alexa Christophides1Zhaosheng Jin2Murad Elias3Kamil Taneja4Sergio D. Bergese5Department of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY, United StatesDepartment of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY, United StatesDepartment of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY, United StatesDepartment of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY, United StatesMedical Scientist Training Program, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, United StatesDepartment of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY, United StatesPain refers to the subjective, unpleasant experience that is related to illness or injury. In contrast to pain, nociception refers to the physiological neural processing of noxious stimuli, such as intra-operative surgical stimuli. One novel device, the Analgesia Nociception Index (ANI), aims to objectively measure intra-operative nociception by analyzing the heart rate variability in patients undergoing surgery. Through this method of nociceptive monitoring, the ANI device aims to provide an objective, continuous evaluation of patient comfort levels and allow anesthesiologists to better manage surgical stress and patient analgesia, perhaps with even better efficacy than current practices used to assess nociception. Additionally, ANI may have clinical application in settings outside of the operating room, such as in the intensive care unit. In this narrative review, we compiled and summarized the findings of many studies that have investigated ANI's validity and applications in different clinical settings. Currently, the literature appears mostly supportive of ANI's ability to detect nociception in both surgical and non-surgical settings. However, the ability for ANI to provide clinical benefits, such as decreased intra-operative opioid use, post-operative opioid use, and post-operative pain compared to standard practices appear controversial. Because of the wide variety of methodology, clinical settings, patient populations, and limitations in these studies, more investigation of ANI is needed before any firm conclusions can be drawn on its clinical benefits.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1234246/fullanalgesianociceptionanalgesia nociception indexmonitoringpain |
| spellingShingle | Bill Hum Alexa Christophides Zhaosheng Jin Murad Elias Kamil Taneja Sergio D. Bergese The validity and applications of the analgesia nociception index: a narrative review Frontiers in Surgery analgesia nociception analgesia nociception index monitoring pain |
| title | The validity and applications of the analgesia nociception index: a narrative review |
| title_full | The validity and applications of the analgesia nociception index: a narrative review |
| title_fullStr | The validity and applications of the analgesia nociception index: a narrative review |
| title_full_unstemmed | The validity and applications of the analgesia nociception index: a narrative review |
| title_short | The validity and applications of the analgesia nociception index: a narrative review |
| title_sort | validity and applications of the analgesia nociception index a narrative review |
| topic | analgesia nociception analgesia nociception index monitoring pain |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1234246/full |
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