A novel biomarker of fibrofatty replacement in dystrophinopathies identified by integrating transcriptome, magnetic resonance imaging, and pathology data

A novel biomarker of fibrofatty replacement in dystrophinopathies identified by integrating transcriptome, magnetic resonance imaging, and pathology data

Abstract Background We aimed to analyse genome‐wide transcriptome differences between Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) patients and identify biomarkers that correlate well with muscle magnetic resonance imaging (MRI) and histological fibrofatty replacement in bot...

Full description

Bibliographic Details
Main Authors: Zhihao Xie, Chang Liu, Chengyue Sun, Yanyu Lu, Shiyi Wu, Yilin Liu, Qi Wang, Yalan Wan, Yikang Wang, Meng Yu, Lingchao Meng, Jianwen Deng, Wei Zhang, Zhaoxia Wang, Chunxia Yang, Yun Yuan, Zhiying Xie
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Becker muscular dystrophy
Duchenne muscular dystrophy
Fibrofatty replacement
Transcriptome
Online Access:https://doi.org/10.1002/jcsm.13410

Internet

https://doi.org/10.1002/jcsm.13410

Similar Items