EML4-ALK Fusion Lung Cancer: A Rare Acquired Event

EML4-ALK Fusion Lung Cancer: A Rare Acquired Event

A recurrent gene fusion between EML4 and ALK in 6.7% of non-small cell lung cancers (NSCLCs) and NKX2-1 (TTF1, TITF1) high-level amplifications in 12% of adenocarcinomas of the lung were independently reported recently. Because the EML4-ALK fusion was only shown by a reverse transcription-polymerase...

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Bibliographic Details
Main Authors: Sven Perner, Patrick L Wagner, Francesca Demichelis, Rohit Mehra, Christopher J LaFargue, Benjamin J Moss, Stefanie Arbogast, Alex Soltermann, Walter Weder, Thomas J Giordano, David G Beer, David S Rickman, Arul M Chinnaiyan, Holger Moch, Mark A Rubin
Format: Article
Language:English
Published: Elsevier 2008-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608801261

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http://www.sciencedirect.com/science/article/pii/S1476558608801261

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