Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD.

<h4>Background</h4>Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death worldwide. Neutrophilic inflammation is prominent, worsened during infective exacerbations and is refractory to glucocorticosteroids (GCs). Deregulated neutrophilic inflammation...

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Bibliographic Details
Main Authors: Ross Vlahos, Peter A B Wark, Gary P Anderson, Steven Bozinovski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22413009/?tool=EBI