Behavioral and neurochemical deficits in aging rats with increased neonatal iron intake: silibinin’s neuroprotection by maintaining redox balance

Aging is a critical risk factor for Parkinson’s disease. Silibinin, a major flavonoid in Silybum marianum, has been suggested to display neuroprotective properties against various neurodegenerative diseases. In the present study, we observed that neonatal iron (120 μg/g body weight) supplementation...

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Bibliographic Details
Main Authors: Hanqing eChen, Xijin eWang, Meihua eWang, Liu eYang, Zhiqiang eYan, Yuhong eZhang, Zhenguo eLiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00206/full