A hypothesis for using pathway genetic load analysis for understanding complex outcomes in bilirubin encephalopathy

Genetic-based susceptibility to bilirubin neurotoxicity and chronic bilirubin encephalopathy (kernicterus) is still poorly understood. Neonatal jaundice affects 60-80% of newborns, and considerable effort goes into preventing this relatively benign condition from escalating into the development of k...

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Bibliographic Details
Main Authors: Sean M. Riordan, Douglas C. Bittel, Jean-Baptiste LePichon, Silvia Gazzin, Claudio Tiribelli, Jon F Watchko, Richard P. Wennberg, Steven M. Shapiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00376/full