Diabetes Primes Neutrophils for Neutrophil Extracellular Trap Formation through Trained Immunity

Diabetes Primes Neutrophils for Neutrophil Extracellular Trap Formation through Trained Immunity

Neutrophils are primed for neutrophil extracellular trap (NET) formation during diabetes, and excessive NET formation from primed neutrophils compromises wound healing in patients with diabetes. Here, we demonstrate that trained immunity mediates diabetes-induced NET priming in neutrophils. Under di...

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Bibliographic Details
Main Authors: Sanjeeb Shrestha, Yu-Bin Lee, Hoyul Lee, Yeon-Kyung Choi, Bo-Yoon Park, Mi-Jin Kim, Young-Jin Youn, Sun-Hwa Kim, Soo-Jung Jung, Dong-Keun Song, Hee Kyung Jin, Jae-Sung Bae, In-Kyu Lee, Jae-Han Jeon, Chang-Won Hong
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2024-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0365

Internet

https://spj.science.org/doi/10.34133/research.0365

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