Molecular mechanisms of naringenin modulation of mitochondrial permeability transition acting on F1FO-ATPase and counteracting saline load-induced injury in SHRSP cerebral endothelial cells

Molecular mechanisms of naringenin modulation of mitochondrial permeability transition acting on F1FO-ATPase and counteracting saline load-induced injury in SHRSP cerebral endothelial cells

Naringenin (NRG) was characterized for its ability to counteract mitochondrial dysfunction which is linked to cardiovascular diseases. The F1FO-ATPase can act as a molecular target of NRG. The interaction of NRG with this enzyme can avoid the energy transmission mechanism of ATP hydrolysis, especial...

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Bibliographic Details
Main Authors: Salvatore Nesci, Cristina Algieri, Matteo Antonio Tallarida, Rosita Stanzione, Saverio Marchi, Donatella Pietrangelo, Fabiana Trombetti, Luca D’Ambrosio, Maurizio Forte, Maria Cotugno, Ilaria Nunzi, Rachele Bigi, Loredana Maiuolo, Antonio De Nino, Paolo Pinton, Giovanni Romeo, Speranza Rubattu
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:European Journal of Cell Biology
Subjects:
mitochondria
F1FO-ATPase
naringenin
permeability transition pore
ROS
SHRSP
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933524000153

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http://www.sciencedirect.com/science/article/pii/S0171933524000153

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