The Role of Activation of PI3K/AKT/mTOR and RAF/MEK/ERK Pathways in Aggressive Pituitary Adenomas—New Potential Therapeutic Approach—A Systematic Review

The Role of Activation of PI3K/AKT/mTOR and RAF/MEK/ERK Pathways in Aggressive Pituitary Adenomas—New Potential Therapeutic Approach—A Systematic Review

Pituitary tumors (PT) are mostly benign, although occasionally they demonstrate aggressive behavior, invasion of surrounding tissues, rapid growth, resistance to conventional treatments, and multiple recurrences. The pathogenesis of PT is still not fully understood, and the factors responsible for i...

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Bibliographic Details
Main Authors: Aleksandra Derwich, Monika Sykutera, Barbara Bromińska, Błażej Rubiś, Marek Ruchała, Nadia Sawicka-Gutaj
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
pituitary tumor
aggressive pituitary adenoma
RAF/MEK/ERK pathway
PI3K/AKT/mTOR pathway
Online Access:https://www.mdpi.com/1422-0067/24/13/10952

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https://www.mdpi.com/1422-0067/24/13/10952

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