A CpG island-encoded mechanism protects genes from premature transcription termination

A CpG island-encoded mechanism protects genes from premature transcription termination

Here the authors discover that SET1 complexes function as transcription anti-termination factors that bind to CpG islands and protect low to moderately transcribed genes from the pervasive termination activity of the ZC3H4 complex.

Bibliographic Details
Main Authors: Amy L. Hughes, Aleksander T. Szczurek, Jessica R. Kelley, Anna Lastuvkova, Anne H. Turberfield, Emilia Dimitrova, Neil P. Blackledge, Robert J. Klose
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36236-2

Internet

https://doi.org/10.1038/s41467-023-36236-2

Similar Items