Antibody Subclass and Glycosylation Shift Following Effective TB Treatment

Antibody Subclass and Glycosylation Shift Following Effective TB Treatment

With an estimated 25% of the global population infected with Mycobacterium tuberculosis (Mtb), tuberculosis (TB) remains a leading cause of death by infectious diseases. Humoral immunity following TB treatment is largely uncharacterized, and antibody profiling could provide insights into disease res...

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Bibliographic Details
Main Authors: Patricia S. Grace, Sepideh Dolatshahi, Lenette L. Lu, Adam Cain, Fabrizio Palmieri, Linda Petrone, Sarah M. Fortune, Tom H. M. Ottenhoff, Douglas A. Lauffenburger, Delia Goletti, Simone A. Joosten, Galit Alter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
antibodies
tuberculosis
IgG4
Fc-glycosylation
TB therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.679973/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.679973/full

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