Fluid shear stress sensitizes cancer cells to receptor-mediated apoptosis via trimeric death receptors

Cancer metastasis, the process of cancer cell migration from a primary to distal location, typically leads to a poor patient prognosis. Hematogenous metastasis is initiated by intravasation of circulating tumor cells (CTCs) into the bloodstream, which are then believed to adhere to the luminal surfa...

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Bibliographic Details
Main Authors: Michael J Mitchell, Michael R King
Format: Article
Language:English
Published: IOP Publishing 2013-01-01
Series:New Journal of Physics
Online Access:https://doi.org/10.1088/1367-2630/15/1/015008