Crosstalk between KDEL receptor and EGF receptor mediates cell proliferation and migration via STAT3 signaling

Crosstalk between KDEL receptor and EGF receptor mediates cell proliferation and migration via STAT3 signaling

Abstract Hostile microenvironment of cancer cells provoke a stressful condition for endoplasmic reticulum (ER) and stimulate the expression and secretion of ER chaperones, leading to tumorigenic effects. However, the molecular mechanism underlying these effects is largely unknown. In this study, we...

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Bibliographic Details
Main Authors: Jie Jia, Lianhui Zhu, Xihua Yue, Shuocheng Tang, Shuaiyang Jing, Chuanting Tan, Yulei Du, Jingkai Gao, Intaek Lee, Yi Qian
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Communication and Signaling
Subjects:
KDEL receptor
EGF receptor
STAT3
GRP78
ERp57
Golgi
Online Access:https://doi.org/10.1186/s12964-024-01517-w

Internet

https://doi.org/10.1186/s12964-024-01517-w

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