Structural Factors That Determine the Activity of the Xenobiotic Reductase B Enzyme from <i>Pseudomonas putida</i> on Nitroaromatic Compounds

Structural Factors That Determine the Activity of the Xenobiotic Reductase B Enzyme from <i>Pseudomonas putida</i> on Nitroaromatic Compounds

Xenobiotic reductase B (XenB) catalyzes the reduction of the aromatic ring or nitro groups of nitroaromatic compounds with methyl, amino or hydroxyl radicals. This reaction is of biotechnological interest for bioremediation, the reuse of industrial waste or the activation of prodrugs. However, the s...

Full description

Bibliographic Details
Main Authors: Manuel I. Osorio, Nicolás Bruna, Víctor García, Lisdelys González-Rodríguez, Matías S. Leal, Francisco Salgado, Matías Vargas-Reyes, Fernando González-Nilo, José M. Pérez-Donoso, Osvaldo Yáñez
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
molecular dynamics simulation
quantum mechanics
substrate promiscuity of enzymes
nitroaromatic compound reactivity
protein–ligand interactions
Online Access:https://www.mdpi.com/1422-0067/24/1/400

Internet

https://www.mdpi.com/1422-0067/24/1/400

Similar Items