Icariin promotes osteogenic differentiation by upregulating alpha-enolase expression

Icariin promotes osteogenic differentiation by upregulating alpha-enolase expression

Osteogenic differentiation is a crucial biological process for maintaining bone remodelling. Aerobic glycolysis is the main source of energy for osteogenic differentiation. Alpha-enolase (Eno1), a glycolytic enzyme, is a therapeutic target for numerous diseases. Icariin, a principal active component...

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Bibliographic Details
Main Authors: Dingbang Xie, Yunteng Xu, Wanping Cai, Junkuan Zhuo, Zaishi Zhu, Haifeng Zhang, Yimin Zhang, Xin Lan, Hui Yan
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Eno1
Aerobic glycolysis
Osteogenic differentiation
Icariin
BMP/Smad4 signalling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823000523

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http://www.sciencedirect.com/science/article/pii/S2405580823000523

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