The influence of sepsis on antimicrobials tissue penetration: The use of microdialysis technique to access free drug distribution

Abstract Sepsis is described as a life-threatening organ dysfunction caused by a host’s response to infection, leading to an unbalance in body homeostasis. It is one of the leading causes of death in developed countries. Considering that in critically ill patients, such as those with sepsis, plasma...

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Bibliographic Details
Main Authors: Karolina Torres Santos-Borges, Pricilla Henz, Bibiana Verlindo de Araújo
Format: Article
Language:English
Published: Universidade de São Paulo 2023-11-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502023000100420&tlng=en