The BNT162b2 vaccine induces humoral and cellular immune memory to SARS-CoV-2 Wuhan strain and the Omicron variant in children 5 to 11 years of age

The BNT162b2 vaccine induces humoral and cellular immune memory to SARS-CoV-2 Wuhan strain and the Omicron variant in children 5 to 11 years of age

SARS-CoV-2 mRNA vaccines prevent severe COVID-19 by generating immune memory, comprising specific antibodies and memory B and T cells. Although children are at low risk of severe COVID-19, the spreading of highly transmissible variants has led to increasing in COVID-19 cases and hospitalizations als...

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Bibliographic Details
Main Authors: Bianca Laura Cinicola, E Piano Mortari, Anna Maria Zicari, Chiara Agrati, Veronica Bordoni, Christian Albano, Giorgio Fedele, Ilaria Schiavoni, Pasqualina Leone, Stefano Fiore, Martina Capponi, Maria Giulia Conti, Laura Petrarca, Paola Stefanelli, Alberto Spalice, Fabio Midulla, Anna Teresa Palamara, Isabella Quinti, Franco Locatelli, Rita Carsetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
Omicron
vaccine
children
immune memory
memory B cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1094727/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1094727/full

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