Nickel-catalyzed asymmetric hydrogenation for the preparation of α-substituted propionic acids

Abstract Transition metal-catalyzed asymmetric hydrogenation is one of the most efficient methods for the preparation of chiral α-substituted propionic acids. However, research on this method, employing cleaner earth-abundant metal catalysts, is still insufficient in both academic and industrial con...

Full description

Bibliographic Details
Main Authors: Bowen Li, Zhiling Wang, Yicong Luo, Hanlin Wei, Jianzhong Chen, Delong Liu, Wanbin Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-49801-0