Age and 17β-Estradiol (E<sub>2</sub>) Facilitate Nuclear Export and Argonaute Loading of microRNAs in the Female Brain

Age and 17β-Estradiol (E<sub>2</sub>) Facilitate Nuclear Export and Argonaute Loading of microRNAs in the Female Brain

Aging in women is accompanied by a dramatic change in circulating sex steroid hormones. Specifically, the primary circulating estrogen, 17β-estradiol (E<sub>2</sub>), is nearly undetectable in post-menopausal women. This decline is associated with a variety of cognitive and mood disorder...

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Detalhes bibliográficos
Principais autores: Megan L. Linscott, Yoldas Yildiz, Sarah Flury, Mikayla L. Newby, Toni R. Pak
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2023-12-01
coleção:Non-Coding RNA
Assuntos:
microRNA
RNA binding proteins
hnRNPA1
argonaute
estradiol
hypothalamus
Acesso em linha:https://www.mdpi.com/2311-553X/9/6/74

Internet

https://www.mdpi.com/2311-553X/9/6/74

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