Advanced pharmacodynamics of cangrelor in healthy volunteers: a dose-finding, open-label, pilot trial

Advanced pharmacodynamics of cangrelor in healthy volunteers: a dose-finding, open-label, pilot trial

Abstract Background High on-treatment platelet reactivity (HTPR) remains a major problem in the acute management of ST-elevation myocardial infarction (STEMI), leading to higher rates of stent thrombosis and mortality. We aimed to investigate a novel, prehospital treatment strategy using cangrelor a...

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Bibliographic Details
Main Authors: Georg Gelbenegger, Juergen Grafeneder, Gloria M. Gager, Jolanta M. Siller-Matula, Michael Schwameis, Bernd Jilma, Christian Schoergenhofer
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Thrombosis Journal
Subjects:
Platelet inhibition
Cangrelor
Prehospital
P2Y12
Pharmacodynamics
Myocardial infarction
Online Access:https://doi.org/10.1186/s12959-022-00377-z

Internet

https://doi.org/10.1186/s12959-022-00377-z

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