Protein Abundance of Drug Transporters in Human Hepatitis C Livers

Protein Abundance of Drug Transporters in Human Hepatitis C Livers

Transmembrane drug transport in hepatocytes is one of the major determinants of drug pharmacokinetics. In the present study, ABC transporters (P-gp, MRP1, MRP2, MRP3, MRP4, BCRP, and BSEP) and SLC transporters (MCT1, NTCP, OAT2, OATP1B1, OATP1B3, OATP2B1, OCT1, and OCT3) were quantified for protein...

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Bibliographic Details
Main Authors: Marek Droździk, Joanna Lapczuk-Romanska, Christoph Wenzel, Łukasz Skalski, Sylwia Szeląg-Pieniek, Mariola Post, Marta Syczewska, Mateusz Kurzawski, Stefan Oswald
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
hepatitis C
liver
cirrhosis
Child–Pugh score
drug transporter
protein quantification
Online Access:https://www.mdpi.com/1422-0067/23/14/7947

Internet

https://www.mdpi.com/1422-0067/23/14/7947

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