Assessing translational applicability of perineuronal net dysfunction in Alzheimer’s disease across species

In the context of aging and age-associated neurodegenerative disorders, the brain’s extracellular matrix (ECM) serves as a critical regulator for neuronal health and cognitive function. Within the extracellular space, proteoglycans and their glycosaminoglycan attachments play essential roles in form...

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Bibliographic Details
Main Authors: Aarun S. Hendrickson, Kendra L. Francis, Asmit Kumar, Jaden P. Le, Jarrad M. Scarlett, C. Dirk Keene, David A. Tovar, Kimberly M. Alonge
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1396101/full