Comprehensive analyses of the cancer-associated fibroblast subtypes and their score system for prediction of outcomes and immunosuppressive microenvironment in prostate cancer

Comprehensive analyses of the cancer-associated fibroblast subtypes and their score system for prediction of outcomes and immunosuppressive microenvironment in prostate cancer

Abstract Background Cancer-associated fibroblasts (CAFs) drive cancer progression and treatment failure on one hand, while their tumor-restraining functions are also observed on the other. Recent single cell RNA sequencing (scRNA-seq) analyses demonstrates heterogeneity of CAFs and defines molecular...

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Bibliographic Details
Main Authors: Ze Gao, Ning Zhang, Bingzheng An, Dawei Li, Zhiqing Fang, Dawei Xu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Cancer Cell International
Subjects:
Caner associated fibroblasts
Immunotherapy
Prostate cancer
Tumor microenvironment
Tumor progression
Online Access:https://doi.org/10.1186/s12935-024-03305-5

Internet

https://doi.org/10.1186/s12935-024-03305-5

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