Targeting Metabolism in Cancer Cells and the Tumour Microenvironment for Cancer Therapy

Targeting Metabolism in Cancer Cells and the Tumour Microenvironment for Cancer Therapy

Targeting altered tumour metabolism is an emerging therapeutic strategy for cancer treatment. The metabolic reprogramming that accompanies the development of malignancy creates targetable differences between cancer cells and normal cells, which may be exploited for therapy. There is also emerging ev...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Jiaqi Li, Jie Qing Eu, Li Ren Kong, Lingzhi Wang, Yaw Chyn Lim, Boon Cher Goh, Andrea L. A. Wong
Natura:	Articolo
Lingua:	English
Pubblicazione:	MDPI AG 2020-10-01
Serie:	Molecules
Soggetti:	cancer cell metabolism tumour microenvironment metabolic reprogramming targeted therapy immunotherapy
Accesso online:	https://www.mdpi.com/1420-3049/25/20/4831

Documenti analoghi

Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment
di: Dongki Yang, et al.
Pubblicazione: (2019-03-01)

Metabolism, metabolites, and macrophages in cancer
di: Mengyuan Li, et al.
Pubblicazione: (2023-07-01)

Metabolic reprogramming of the tumor immune microenvironment in ovarian cancer: A novel orientation for immunotherapy
di: Yi Lin, et al.
Pubblicazione: (2022-10-01)

Targeting T cell immunometabolism for cancer immunotherapy; understanding the impact of the tumour microenvironment
di: Mary B Mockler, et al.
Pubblicazione: (2014-05-01)

Metabolic reprogramming and immune evasion: the interplay in the tumor microenvironment
di: Haixia Zhang, et al.
Pubblicazione: (2024-09-01)

Autonomous glucose metabolic reprogramming of tumour cells under hypoxia: opportunities for targeted therapy
di: Mingyao Huang, et al.
Pubblicazione: (2020-09-01)

Advances in macrophage and T cell metabolic reprogramming and immunotherapy in the tumor microenvironment
di: Hua Cheng, et al.
Pubblicazione: (2024-01-01)

Glucose metabolism and tumour microenvironment in pancreatic cancer: A key link in cancer progression
di: Shi Dong, et al.
Pubblicazione: (2022-12-01)

Metabolic reprogramming and crosstalk of cancer-related fibroblasts and immune cells in the tumor microenvironment
di: Yifei Zhu, et al.
Pubblicazione: (2022-08-01)

Lighting Up the Fire in the Microenvironment of Cold Tumors: A Major Challenge to Improve Cancer Immunotherapy
di: Alice Benoit, et al.
Pubblicazione: (2023-07-01)

Unlocking the potential of T‐cell metabolism reprogramming: Advancing single‐cell approaches for precision immunotherapy in tumour immunity
di: Lihaoyun Huang, et al.
Pubblicazione: (2024-03-01)

Analyzing the impact of metabolism on immune cells in tumor microenvironment to promote the development of immunotherapy
di: Yanru Long, et al.
Pubblicazione: (2024-01-01)

Targeting cancer-specific metabolic pathways for developing novel cancer therapeutics
di: Soumik Pal, et al.
Pubblicazione: (2022-12-01)

Identification of a novel lipid metabolism-related gene signature within the tumour immune microenvironment for breast cancer
di: Xu Chang, et al.
Pubblicazione: (2022-05-01)

Metabolic Reprogramming of Thyroid Cancer Cells and Crosstalk in Their Microenvironment
di: Lisha Bao, et al.
Pubblicazione: (2021-12-01)

Mechanisms of HIF-driven immunosuppression in tumour microenvironment
di: Shinjini Bandopadhyay, et al.
Pubblicazione: (2023-08-01)

The roles of epigallocatechin gallate in the tumor microenvironment, metabolic reprogramming, and immunotherapy
di: Dongming Li, et al.
Pubblicazione: (2024-01-01)

Metabolic reprogramming and immunological changes in the microenvironment of esophageal cancer: future directions and prospects
di: Zhi-Xun Guo, et al.
Pubblicazione: (2025-01-01)

Targeting lipid metabolism reprogramming of immunocytes in response to the tumor microenvironment stressor: A potential approach for tumor therapy
di: Ming Zhang, et al.
Pubblicazione: (2022-09-01)

Glycolysis in the tumor microenvironment: a driver of cancer progression and a promising therapeutic target
di: Junpeng Zhao, et al.
Pubblicazione: (2024-06-01)

Fine-Tuning the Tumour Microenvironment: Current Perspectives on the Mechanisms of Tumour Immunosuppression
di: Jesse D. Armitage, et al.
Pubblicazione: (2021-01-01)

Effect of neoadjuvant chemotherapy on the immune microenvironment of gynaecological tumours
di: Jing Xue, et al.
Pubblicazione: (2023-12-01)

Unveiling the functional roles of patient‐derived tumour organoids in assessing the tumour microenvironment and immunotherapy
di: Di Chen, et al.
Pubblicazione: (2024-09-01)

A signature based on circadian rhythm-associated genes for the evaluation of prognosis and the tumour microenvironment in HNSCC
di: Changqian Wang, et al.
Pubblicazione: (2024-03-01)

Editorial: Molecular biomarkers and imaging markers in the prediction, diagnosis, and prognosis of bladder cancer
di: Yongwen Luo, et al.
Pubblicazione: (2022-10-01)

Advances in reprogramming of energy metabolism in tumor T cells
di: Liu Xuekai, et al.
Pubblicazione: (2024-02-01)

Involvement of tumor immune microenvironment metabolic reprogramming in colorectal cancer progression, immune escape, and response to immunotherapy
di: Andrea Nicolini, et al.
Pubblicazione: (2024-07-01)

Bicarbonate transport as regulator of antitumour immunity in pancreatic cancer
di: Emily J. Kay, et al.
Pubblicazione: (2023-04-01)

Nanomedicines Targeting Metabolism in the Tumor Microenvironment
di: Mengdi Ren, et al.
Pubblicazione: (2022-08-01)

Editorial: Tumor metabolic microenvironment: one man’s meat is another man’s poison
di: Jing Xu, et al.
Pubblicazione: (2024-05-01)

Targeting tumour microenvironment by tyrosine kinase inhibitor
di: Hor-Yue Tan, et al.
Pubblicazione: (2018-02-01)

m6A methylation: a process reshaping the tumour immune microenvironment and regulating immune evasion
di: Xiaoxue Cao, et al.
Pubblicazione: (2023-03-01)

Choline metabolism reprogramming mediates an immunosuppressive microenvironment in non-small cell lung cancer (NSCLC) by promoting tumor-associated macrophage functional polarization and endothelial cell proliferation
di: Bijing Xiao, et al.
Pubblicazione: (2024-05-01)

High-ammonia microenvironment promotes stemness and metastatic potential in hepatocellular carcinoma through metabolic reprogramming
di: Renchao Zou, et al.
Pubblicazione: (2025-02-01)

Editorial: Tumor microenvironment and metabolic reprogramming in cancer
di: Xiaoling Cui, et al.
Pubblicazione: (2024-10-01)

Metabolic reprogramming in the tumor microenvironment of liver cancer
di: Jian Lin, et al.
Pubblicazione: (2024-01-01)

LncRNAs in tumor metabolic reprogramming and tumor microenvironment remodeling
di: Jianhang Jiao, et al.
Pubblicazione: (2024-10-01)

Macrophage metabolic reprogramming and atherosclerotic plaque microenvironment: Fostering each other?
di: Qi Xiao, et al.
Pubblicazione: (2023-05-01)

A review of lactate-lactylation in malignancy: its potential in immunotherapy
di: Jinhui Zha, et al.
Pubblicazione: (2024-05-01)

Metabolic Remodeling in Glioma Immune Microenvironment: Intercellular Interactions Distinct From Peripheral Tumors
di: Runze Qiu, et al.
Pubblicazione: (2021-06-01)