Optochemical Control of Immune Checkpoint Blockade via Light‐Triggered PD‐L1 Dimerization

Optochemical Control of Immune Checkpoint Blockade via Light‐Triggered PD‐L1 Dimerization

The blockade of PD‐1/PD‐L1, which serves to “release the brake” of tumor immunity, represents a promising approach for treating various malignancies. However, the systemic immune‐related side effects significantly undermine its therapeutic efficacy. To address this dilemma, a photoactivatable and bi...

Full description

Bibliographic Details
Main Authors: Yuwei Liu, Kaiqi Long, Weirong Kang, Tianyi Wang, Weiping Wang
Format: Article
Language:English
Published: Wiley-VCH 2022-06-01
Series:Advanced NanoBiomed Research
Subjects:
immune checkpoint blockade
immunotherapy
PD-L1 dimerization
photopharmacology
photoresponsive prodrug
Online Access:https://doi.org/10.1002/anbr.202200017

Internet

https://doi.org/10.1002/anbr.202200017

Similar Items