The Interaction of TPH2 and 5-HT2A Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study

The Interaction of TPH2 and 5-HT2A Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study

Purpose: TPH2 and 5-HT2A appear to play vital roles in the homeostatic regulation of serotonin levels in the brain, their genetic variations may lead to impaired homeostatic regulation of serotonin resulting in abnormal levels of serotonin in the brain, thus predisposing individuals to MDD. However,...

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Bibliographic Details
Main Authors: Jiarun Yang, Xueyan Zhao, Jingsong Ma, Zhengxue Qiao, Xiuxian Yang, Erying Zhao, Bo Ban, Xiongzhao Zhu, Depin Cao, Yanjie Yang, Xiaohui Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Psychiatry
Subjects:
major depressive disorder
TPH2
5-HT2A
gene-gene interaction
polymorphisms
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00172/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2019.00172/full

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