Altered Balance of Pro-Inflammatory Immune Cells to T Regulatory Cells Differentiates Symptomatic From Asymptomatic Individuals With Anti-Nuclear Antibodies

Altered Balance of Pro-Inflammatory Immune Cells to T Regulatory Cells Differentiates Symptomatic From Asymptomatic Individuals With Anti-Nuclear Antibodies

Systemic Autoimmune Rheumatic Diseases (SARDs) are characterized by the production of anti-nuclear antibodies (ANAs). ANAs are also seen in healthy individuals and can be detected years before disease onset in SARD. Both the immunological changes that promote development of clinical symptoms in SARD...

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Bibliographic Details
Main Authors: Rashi Gupta, Emma Vanlieshout, Kieran Manion, Dennisse Bonilla, Michael Kim, Carolina Muñoz-Grajales, Carol Nassar, Sindhu R. Johnson, Linda T. Hiraki, Zareen Ahmad, Zahi Touma, Arthur Bookman, Joan E. Wither
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
b cells
monocytes
t cells
dendritic cells
anti-nuclear antibodies
systemic autoimmune rheumatic diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.886442/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.886442/full

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