Early Detection of Cartilage Degeneration: A Comparison of Histology, Fiber Bragg Grating-Based Micro-Indentation, and Atomic Force Microscopy-Based Nano-Indentation

Early Detection of Cartilage Degeneration: A Comparison of Histology, Fiber Bragg Grating-Based Micro-Indentation, and Atomic Force Microscopy-Based Nano-Indentation

We have determined the sensitivity and detection limit of a new fiber Bragg grating (FBG)-based optoelectronic micro-indenter for biomechanical testing of cartilage and compared the results to indentation-type atomic force microscopy (IT-AFM) and histological staining. As test samples, we used bovin...

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Bibliographic Details
Main Authors: Bastian Hartmann, Gabriele Marchi, Paolo Alberton, Zsuzsanna Farkas, Attila Aszodi, Johannes Roths, Hauke Clausen-Schaumann
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
FBG sensor
FBGindentation-type atomic force microscopy
FBGearly detection of osteoarthritis
FBGoptical biosensor
FBGbiomechanics of cartilage
Online Access:https://www.mdpi.com/1422-0067/21/19/7384

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https://www.mdpi.com/1422-0067/21/19/7384

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