Effect of maternal periconceptional undernutrition in sheep on cortisol regulation in offspring from mid-late gestation, through to adulthood

Effect of maternal periconceptional undernutrition in sheep on cortisol regulation in offspring from mid-late gestation, through to adulthood

IntroductionMaternal periconceptional undernutrition (PCUN) alters fetal hypothalamic-pituitary-adrenal axis (HPAA) function and placental glucocorticoid metabolism in sheep. The effects of PCUN on HPAA function in adult life are not known. We investigated the effects of PCUN on fetal adrenal develo...

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Bibliographic Details
Main Authors: Mark H. Oliver, Anne L. Jaquiery, Kristin L. Connor, Hui Hui Phua, Jane E. Harding, Eric B. Thorstensen, Frank H. Bloomfield
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Endocrinology
Subjects:
programming
long-term
outcomes
adrenal
cortisol
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1122432/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1122432/full

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