Anoikis resistance and immune escape mediated by Epstein-Barr virus-encoded latent membrane protein 1-induced stabilization of PGC-1α promotes invasion and metastasis of nasopharyngeal carcinoma

Anoikis resistance and immune escape mediated by Epstein-Barr virus-encoded latent membrane protein 1-induced stabilization of PGC-1α promotes invasion and metastasis of nasopharyngeal carcinoma

Abstract Background Epstein-Barr virus (EBV) is the first discovered human tumor virus that is associated with a variety of malignancies of both lymphoid and epithelial origin including nasopharyngeal carcinoma (NPC). The EBV-encoded latent membrane protein 1 (LMP1) has been well-defined as a potent...

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Bibliographic Details
Main Authors: Chaoliang Liao, Min Li, Xue Chen, Chenpeng Tang, Jing Quan, Ann M. Bode, Ya Cao, Xiangjian Luo
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
LMP1
PGC-1α
Anoikis resistance
Immune escape
Nasopharyngeal carcinoma
Online Access:https://doi.org/10.1186/s13046-023-02835-6

Internet

https://doi.org/10.1186/s13046-023-02835-6

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