Crosstalk between Different DNA Repair Pathways Contributes to Neurodegenerative Diseases

Crosstalk between Different DNA Repair Pathways Contributes to Neurodegenerative Diseases

Genomic integrity is maintained by DNA repair and the DNA damage response (DDR). Defects in certain DNA repair genes give rise to many rare progressive neurodegenerative diseases (NDDs), such as ocular motor ataxia, Huntington disease (HD), and spinocerebellar ataxias (SCA). Dysregulation or dysfunc...

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Bibliographic Details
Main Authors: Swapnil Gupta, Panpan You, Tanima SenGupta, Hilde Nilsen, Kulbhushan Sharma
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biology
Subjects:
neurodegeneration
DNA damage response
oxidative stress
PARP
ALS
Alzheimer
Online Access:https://www.mdpi.com/2079-7737/10/2/163

Internet

https://www.mdpi.com/2079-7737/10/2/163

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