ST08 Altered NF-κB Pathway in Breast Cancer Cells In Vitro as Revealed by miRNA-mRNA Analysis and Enhanced the Effect of Cisplatin on Tumour Reduction in EAC Mouse Model

ST08 Altered NF-κB Pathway in Breast Cancer Cells In Vitro as Revealed by miRNA-mRNA Analysis and Enhanced the Effect of Cisplatin on Tumour Reduction in EAC Mouse Model

ST08 is a novel curcumin derivative that exhibited apoptotic and anti-migratory activity in MDA-MB-231, triple-negative breast cancer cells reported earlier. In this study, we further explored the anticancer properties of ST08. ST08 reduced tumor burden in vivo and induced apoptosis through the mito...

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Bibliographic Details
Main Authors: Snehal Nirgude, Sagar Desai, Raghunandan Mahadeva, Febina Ravindran, Bibha Choudhary
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
integrated transcriptomic approach
synergistic
tumor regression
Curcumin derivatives
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.835027/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.835027/full

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