Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting

<p>Abstract</p> <p>Background</p> <p>Testicular germ cell tumors (TGCTs) are classified as seminonas or non-seminomas of which a major subset is embryonal carcinoma (EC) that can differentiate into diverse tissues. The pluripotent nature of human ECs resembles that of e...

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Bibliographic Details
Main Authors: Bee Thomas, Ewings Katherine E, Schwarz Elisabeth, Busch Alexander M, Kasper Allison C, Snow Grace E, Spinella Michael J, Dmitrovsky Ethan, Freemantle Sarah J
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/383