Heme Signaling Impacts Global Gene Expression, Immunity and Dengue Virus Infectivity in Aedes aegypti.

Heme Signaling Impacts Global Gene Expression, Immunity and Dengue Virus Infectivity in Aedes aegypti.

Blood-feeding mosquitoes are exposed to high levels of heme, the product of hemoglobin degradation. Heme is a pro-oxidant that influences a variety of cellular processes. We performed a global analysis of heme-regulated Aedes aegypti (yellow fever mosquito) transcriptional changes to better understa...

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Bibliographic Details
Main Authors: Vanessa Bottino-Rojas, Octávio A C Talyuli, Natapong Jupatanakul, Shuzhen Sim, George Dimopoulos, Thiago M Venancio, Ana C Bahia, Marcos H Sorgine, Pedro L Oliveira, Gabriela O Paiva-Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4537099?pdf=render

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http://europepmc.org/articles/PMC4537099?pdf=render

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