Selenite Induces Cell Cycle Arrest and Apoptosis via Reactive Oxygen Species-Dependent Inhibition of the AKT/mTOR Pathway in Thyroid Cancer

Thyroid cancer is the most common endocrine malignancy, and its incidence has increased in the past decades. Selenium has been shown to have therapeutic effects against several tumors. However, its role in thyroid cancer and its underlying molecular mechanism remains to be explored. In the present s...

Full description

Bibliographic Details
Main Authors: Zhen Cheng, Shuang Yu, Weiman He, Jie Li, Tianyi Xu, Junyu Xue, Peijie Shi, Shuwei Chen, Yanbing Li, Shubin Hong, Haipeng Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.668424/full