LINC00924-induced fatty acid metabolic reprogramming facilitates gastric cancer peritoneal metastasis via hnRNPC-regulated alternative splicing of Mnk2

LINC00924-induced fatty acid metabolic reprogramming facilitates gastric cancer peritoneal metastasis via hnRNPC-regulated alternative splicing of Mnk2

Abstract The molecular mechanism underlying gastric cancer (GC) peritoneal metastasis (PM) remains unclear. Here, we identified LINC00924 as a GC PM-related lncRNA through Microarray sequencing. LINC00924 was highly expressed in GC, and its high expression is associated with a broad range of PM. Via...

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Bibliographic Details
Main Authors: Qiuming He, Chaogang Yang, Zhenxian Xiang, Guoquan Huang, Haitao Wu, Tingna Chen, Rongzhang Dou, Jialing Song, Lei Han, TianTian Song, Shuyi Wang, Bin Xiong
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05436-x

Internet

https://doi.org/10.1038/s41419-022-05436-x

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