Low oxygen tension increases mitochondrial membrane potential and enhances expression of antioxidant genes and implantation protein of mouse blastocyst cultured in vitro

Low oxygen tension increases mitochondrial membrane potential and enhances expression of antioxidant genes and implantation protein of mouse blastocyst cultured in vitro

Abstract Background In human IVF, embryos cultured with a lower O2 tension (5%) can give rise to higher success rates when compared with normoxic conditions (20%). However, the mechanisms behind the beneficial effects of reduced oxygen tension in embryogenesis remain unclear. The aim of this study w...

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Bibliographic Details
Main Authors: Yun-Yi Ma, Huei-Wen Chen, Chii-Ruey Tzeng
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Ovarian Research
Subjects:
Antioxidant
Hypoxia
Implantation
Mitochondria
Mouse embryo
Online Access:http://link.springer.com/article/10.1186/s13048-017-0344-1

Internet

http://link.springer.com/article/10.1186/s13048-017-0344-1

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