ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy

ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy

Summary: The evolutionarily conserved ULK1 kinase complex acts as gatekeeper of canonical autophagy and regulates induction of autophagosome biogenesis. To better understand control of ULK1 and analyze whether ULK1 has broader functions that are also linked to the later steps of autophagy, we perfor...

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Bibliographic Details
Main Authors: Zehan Hu, Devanarayanan Siva Sankar, Bich Vu, Alexandre Leytens, Christine Vionnet, Wenxian Wu, Michael Stumpe, Esther Martínez-Martínez, Björn Stork, Jörn Dengjel
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
signaling
autophagy
phosphoproteomics
kinase
phosphatase
in vitro kinase assay
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472101216X

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http://www.sciencedirect.com/science/article/pii/S221112472101216X

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