Histone H3 lysine K4 methylation and its role in learning and memory

Abstract Epigenetic modifications such as histone methylation permit change in chromatin structure without accompanying change in the underlying genomic sequence. A number of studies in animal models have shown that dysregulation of various components of the epigenetic machinery causes cognitive def...

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Bibliographic Details
Main Authors: Bridget E. Collins, Celeste B. Greer, Benjamin C. Coleman, J. David Sweatt
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-018-0251-8