Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis

Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis

Abstract Background Hydroxychloroquine (HCQ) has been recommended as a basic treatment for lupus nephritis (LN) during this decade based on its ability to improve LN-related renal immune-mediated inflammatory lesions. As a classical lysosomal inhibitor, HCQ may inhibit lysosomal degradation and disr...

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Bibliographic Details
Main Authors: Ning An, Chen Yang, Hong-Luan Wu, Yun Guo, Xi-Jie Huang, Tong-Sheng Huang, Zhi-Hong Wu, Jing Xue, Rui-Hong Chen, Zhi-Hang Li, Qing-Jun Pan, Hua-Feng Liu
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Arthritis Research & Therapy
Subjects:
Hydroxychloroquine
Lupus nephritis
Proteinuria
Tubular epithelial cells
Acute kidney injury
Repair
Online Access:https://doi.org/10.1186/s13075-021-02700-x

Internet

https://doi.org/10.1186/s13075-021-02700-x

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