Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

<p>Abstract</p> <p>Artesunate (AS) is a clinically versatile artemisinin derivative utilized for the treatment of mild to severe malaria infection. Given the therapeutic significance of AS and the necessity of appropriate AS dosing, substantial research has been performed investiga...

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Bibliographic Details
Main Authors: Shin Chang-Sik, Jung Donald, Borghini-Fuhrer Isabelle, Duparc Stephan, Morris Carrie A, Fleckenstein Lawrence
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/10/1/263