Notch1 signaling impairs regulatory T cells during multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) is a rare pediatric inflammatory disorder characterized by immune cell hyperactivation, cytokine storm, and the production of autoantibodies. The mechanisms underlying such immune dysregulation still need to be unraveled. In this issue of the JCI...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Clinical Investigation
2023-01-01
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| Series: | The Journal of Clinical Investigation |
| Online Access: | https://doi.org/10.1172/JCI166016 |