Mechanisms of HIF-driven immunosuppression in tumour microenvironment

Abstract Hypoxia arises due to insufficient oxygen delivery to rapidly proliferating tumour cells that outpace the available blood supply. It is a characteristic feature of most solid tumour microenvironments and plays a critical role in regulating anti-tumour immunity, enhancing tumoral heterogenei...

Полное описание

Библиографические подробности
Главные авторы: Shinjini Bandopadhyay, Somi Patranabis
Формат: Статья
Язык:English
Опубликовано: SpringerOpen 2023-08-01
Серии:Journal of the Egyptian National Cancer Institute
Предметы:
Online-ссылка:https://doi.org/10.1186/s43046-023-00186-z