Mechanisms of HIF-driven immunosuppression in tumour microenvironment
Abstract Hypoxia arises due to insufficient oxygen delivery to rapidly proliferating tumour cells that outpace the available blood supply. It is a characteristic feature of most solid tumour microenvironments and plays a critical role in regulating anti-tumour immunity, enhancing tumoral heterogenei...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2023-08-01
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Series: | Journal of the Egyptian National Cancer Institute |
Subjects: | |
Online Access: | https://doi.org/10.1186/s43046-023-00186-z |