Mechanisms of hypoxia in the hippocampal CA3 region in postoperative cognitive dysfunction after cardiopulmonary bypass

Mechanisms of hypoxia in the hippocampal CA3 region in postoperative cognitive dysfunction after cardiopulmonary bypass

Abstract Background Postoperative cognitive dysfunction (POCD) is a complication with high morbidity and mortality, commonly observed in the elderly who underwent anesthesia and surgery. The incidence is much higher in cardiac surgery. However, the reason and the mechanism of POCD remains unclear, b...

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Bibliographic Details
Main Authors: Ting Liu, Rui Deng, Xin Wang, Ping Liu, Qiu-Xia Xiao, Qing Liu, Ying Zhang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Cardiopulmonary bypass
Postoperative cognitive dysfunction
Hypoxia
Blood brain barrier
Central nervous system
Online Access:https://doi.org/10.1186/s13019-022-01865-z

Internet

https://doi.org/10.1186/s13019-022-01865-z

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