Docosahexaenoic acid (DHA) prevents atrophy-related signaling in palmitate-treated C2C12 MUSCLE CELLS

Hypertriglyceridemia is a comorbidity of chronic kidney disease (CKD) that contributes to insulin resistance and dysfunctional protein metabolism in skeletal muscle, resulting in debilitating muscle atrophy. The saturated fatty acid palmitate (PA) induces muscle insulin resistance and promotes apopt...

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Bibliographic Details
Main Authors: Myra E. Woodworth-Hobbs, Matthew B. Hudson, Bin Zheng, S. Russ Price
Format: Article
Language:English
Published: The Korean Society of Nephrology 2012-06-01
Series:Kidney Research and Clinical Practice
Online Access:http://www.sciencedirect.com/science/article/pii/S2211913212006572