Contribution of miR-124 rs531564 polymorphism to the occurrence of congenital Zika syndrome

Contribution of miR-124 rs531564 polymorphism to the occurrence of congenital Zika syndrome

Zika virus (ZIKV) cause Congenital Zika Syndrome (CZS) in individuals exposed during pregnancy. Studies have shown that ZIKV infection positively regulates the miR-124 expression in neural cells, which leads to a decrease of TFRC, a gene targeted of this miRNA. Both miR-124 and TFRC exhibit a pivota...

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Bibliographic Details
Main Authors: Julia A Gomes, Igor Araujo Vieira, Eduarda Sgarioni, Ana Cláudia P Terças-Tretell, Juliana H da Silva, Bethânia FR Ribeiro, Marcial F Galera, Thalita M de Oliveira, Maria Denise F Carvalho de Andrade, Isabella F Carvalho, Lavínia Schüler-Faccini, Fernanda SL Vianna
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Epigenetics
Subjects:
maternal exposure
zika virus infection
congenital abnormalities
gene expression
genetic variation
transferrin receptor
micrornas
disease susceptibility
Online Access:http://dx.doi.org/10.1080/15592294.2022.2145061

Internet

http://dx.doi.org/10.1080/15592294.2022.2145061

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